Dr. George Osei Adjei
Head of Department, Medical Laboratory Technology
Dr. George Osei Adjei is a registered member of the America Society for Microbiology (ASM) and Allied Health Professions Council (AHPC), Ghana. He has had training with top-notch institutions such as German Cancer Research Centre, Heidelberg and the Biochemistry Centre, University of Heidelberg, Germany, Noguchi Memorial Institute for Medical Research, Center for Plant Plant Medicine Research, Mampong Akuapem, where he embarked on various researches in the field of Microbiology, Molecular Biology and Biochemistry.
He is a PhD holder in (Clinical Laboratory Diagnostics: Microbiology and Molecular Biology) from the Jiangsu University, P.R. China, School of Medicine, Biochemistry and Molecular Department under the supervision of Prof. Huang Xinxiang.
His career path and progress has been characterised by hard work and dedication to work. From a biology teacher and a research assistant at some point in his life, he joined Accra Technical University as a lecturer in Microbiology, Molecular Diagnostics/Cell Biology and Genetics in July, 2011.
He received his Bachelor of Science (Biological) from the University of Cape Coast and MSc. In Clinical Microbiology from the Kwame Nkrumah University of Science and Technology.
He was the former Head of Department of Science Laboratory Technology in August 2019 to December 2020. He has to his credit over twenty (20) research publications.
1) Osae, R., Alolga, R.N., Essilﬁe, G., Osei-Adjei, G., Baduweh, C.A., Otu, P.N.Y., and Zhou, C. (2020). Variation in bioactive phytochemicals and sensory attributes of osmosonic convective dried ginger from four African countries. J. Sci. Food Agric. 100: pp 3164–3172. DOI 10.1002/jsfa.10351
2) Alolga, R.N., Chavez-Leona, M.A.S.C., Osei-Adjei, G., and Onoja, V. (2019). GC-MS-based metabolomics, antibacterial and anti-inflammatory investigations to characterize the quality of essential oil obtained from dried Xylopia aethiopica fruits from Ghana and Nigeria. Journal of Pharmacy and Pharmacology. 71 pp. 1544–1552. DOI: 10.1111/jphp.13150
3) Zhang, Y., Hu, L., Qiu, Y., Osei-Adjei, G., Tang, H., Zhang, Y., Zhang, Rui., Sheng, X., Xu, S., Yang, H., Yin, Z., Yang, R., Huang, X., and Zhou, D. (2019). QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulence. Environ microbiol. https://doi.org/10.1111/1462-2920.14524
4) Zhang, Y., Chong, X., Xia, L., Lu, R., Osei-Adjei, G., Zhang, Y., and Huang, X. (2018). OxyR positively and directly regulates Vi polysaccharide capsular antigen in Salmonella enterica serovar Typhi. Microb Pathog, DOI: 10.1016/j.micpath.2018.08.050
5) Zhang, Y., Hu, L., Osei-Adjei, G., Zhang, Y., Yang, W., Yin, Z., Lu, R., Sheng, X., Yang, R., Huang, X., and Zhou. D. (2018). Autoregulation of ToxR and its regulatory actions on major virulence gene loci in V. parahaemolyticus. Front. Cell. Infect. Microbiol, 8:291.
6) Osei-Adjei, G., Huang, X., and Zhang, Y. (2018). The extracellular proteases produced by Vibrio parahaemolyticus. World J Microbiol Biotechnol, 34(5):68.
7) Lu, R., Osei-Adjei, G., Huang, X., and Zhang, Y. (2018). Role and regulation of the orphan AphA protein of quorum sensing in pathogenic Vibrios. Future Microbiol, 13:383-391.
8) Zhao, X., Liu R, Tang H., Osei-Adjei, G., Xu, S., Zhang, Y., and Huang, X. (2018). A 3’UTR-derived non-coding RNA RibS increases expression of cfa and promotes biofilm formation in Salmonella enterica serovar Typhi. Res Microbiol, 169(6):279-288.
9) Zhang, Y., Xia, L., Lin, L., Tang, H., Osei-Adjei, G., Xu, S., Zhang, Y., and Huang, X. (2018). Reciprocal regulation of OmpR and Hfq and their regulatory actions on the Vi polysaccharide capsular antigen in Salmonella enterica Serovar Typhi. Curr Microbiol, 75(6):773-778.
10) Osei-Adjei, G., Gao, H., Zhang, Y., Zhang, L., Yang, W., Yang, H., Yin, Z., Huang, X., Zhang, Y., and Zhou, D. (2017). Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus. Oncotarget, 8(39):65809-65822. (SCI, IF = 5.168).
11) Gao, H., Zhang, L., Osei‐Adjei, G., Yang, W., Zhou, D., Huang, X., Yang, H., Yin, Z., and Zhang, Y. (2017). Transcriptional regulation of cpsQ‐mfpABC and mfpABC by CalR in Vibrio parahaemolyticus. Microbiol Open, 6(4): e00470
12) Zhang, L., Osei-Adjei, G., Zhang, Y., Gao, H., Yang, W., Zhou, D., Huang, X., Yang, H., and Zhang, Y. (2017). CalR is required for the expression of T6SS2 and the adhesion of Vibrio parahaemolyticus to HeLa cells. Arch Microbiol, 199(6):931-938.
13) Zhang, Y., Gao, H., Osei-Adjei, G., Zhang, Y., Yang, W., Yang, H., Yin, Z., Huang, X., and Zhou, D. (2017). Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus. Front Microbiol, 8, 2005.
14) Zhang, Y., Yan, D., Xia, L., Zhao, X., Osei-Adjei, G., Xu, S., Sheng, S., and Huang, X. (2016). The malS-5’UTR regulates hisG, a key gene in the histidine biosynthetic pathway in Salmonella enterica serovar Typhi. Can J. Microbiol, 63:287-285.
15) Zhang, Y., Osei-Adjei, G., Ni, B., Fang, H., Zhang, L., Zhao, X., Huang, X., Yang, H., Yang, W., and Sun, F. (2016). Transcription of exsD is repressed directly by H-NS in Vibrio parahaemolyticus. Microb Pathog, 97:221-225.
16) Gordon, A., Asante, S.B., Bukari, Y., Gati, L., Osei-Adjei, G., Hackman, H.K., and Asare, E.O. (2015). Method Development and Validation for Hydroxyurea in Fixed Oral Solid Dosage Forms Using RPHPLC With DAD Detection. J. Applied Res. Vol.1, No.07,235-242
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